Organocatalyzed Intramolecular Carbonyl-Ene Reactions.
نویسندگان
چکیده
An organocatalyzed intramolecular carbonyl-ene reaction was developed to produce carbocyclic and heterocyclic 5- and 6-membered rings from a citronellal-derived trifluoroketone and a variety of aldehydes. A phosphoramide derivative was found to promote the cyclization of the trifluoroketone, whereas a less acidic phosphoric acid proved to be a superior catalyst for the aldehyde substrates.
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ورودعنوان ژورنال:
- Molecules
دوره 21 6 شماره
صفحات -
تاریخ انتشار 2016